UCB (Euronext Brussels: UCB) announced data from two randomized controlled trials showing that treatment with epratuzumab a humanized anti-CD22 antibody, resulted in clinically meaningful reduced disease activity, improved health-related quality of life (HRQoL) measurements and reduced reliance on corticosteroids...
The Lupus Foundation of America (LFA) has awarded more than $1.1 million in new research grants and fellowships as part of its ongoing commitment to bringing down the barriers in developing new treatments and finding a cure for lupus. Lupus is a disabling and life-threatening autoimmune disease that...
Ovarian function can be preserved and disease activity controlled in women with severe systemic lupus erythematosus (SLE) when treated with a 6- month course of cyclophosphamide (CYC), a chemotherapy drug, followed by the immunosuppressant mycophenolate mofetil (MMF), according to a new study presented...
Researchers at the University of New Hampshire Glycomics Center have helped identify a specific carbohydrate structure that confers anti-inflammatory activity to a glycoprotein antibody that could lead to improved treatment of autoimmune diseases like lupus or rheumatoid arthritis. The study, reported...
Preliminary results were released from a late-stage clinical trial of Rituxan (rituximab) for the treatment of lupus. The study did not meet its primary or secondary endpoints of clinically reducing the severity of SLE (systemic lupus erythematosus) in people with moderate disease. The findings are initial...
Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL) announced today that its lead product candidate, R788, has successfully treated lupus prone mice and significantly improved their survival as reported in a recently published study of the drug candidate. R788 (fostamatinib disodium) is an orally bioavailable...
On Tuesday, March 4th, advocates for the Alliance for Lupus Research (ALR), on behalf of the 1.4 million Americans with lupus, described their personal experiences with the disease to their Members of Congress. ALR Advocates visited nearly 100 Congressional offices, representing 21 states, and asked...
It is estimated that as many as 40 percent of all people with the autoimmune disease lupus, and as many as two-thirds of all children with lupus, will develop kidney complications that require medical evaluation and treatment. Because there are so few symptoms of kidney disease, significant damage to...
Learning that your child has a chronic illness is never easy, especially when it’s the unpredictable and potentially fatal autoimmune disease lupus. When it comes to physical activities for children, most parents prefer to err on the side of caution - but medical experts say that may be a mistake....
Immune cells that would normally die in healthy people accumulate in bodies of patients who have lupus and contribute to the disease, according to new Saint Louis University research published in the Feb. 15 issue of Immunity. The finding is important because it tells us more about how lupus develops...
