Hunt For DNA Amplified In Cancers Uncovers Important Target Gene
Researchers at Harvard Medical School (HMS) and Massachusetts General Hospital (MGH) have discovered a new cancer-promoting role for a gene potentially involved in breast, liver, and other kinds of cancers. Their discovery that the gene YAP can transform mammary epithelial cells opens the door to understanding how a novel cell growth controlling pathway first discovered in fruit flies might be important in human cancers. This work is published in the August online early edition of the Proceedings of the National Academy of Sciences and will appear in the Aug. 15 print edition.
