Genmab A/S (OMX: GEN) announced it has completed recruitment of 56 previously untreated follicular non-Hodgkin’s lymphoma (NHL) patients in the Phase II study of ofatumumab (HuMax-CD20(R)) in combination with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP).

“We are happy to finish enrolment in this first study with ofatumumab in front line follicular NHL patients,” said Lisa N. Drakeman, Ph.D., Chief Executive Officer at Genmab. “We look forward to seeing the results of this trial.”

Ofatumumab is an investigational, new generation, human monoclonal antibody that targets a distinct membrane proximal, small loop epitope (specific binding site) of the CD20 molecule on the surface of B-cells. Ofatumumab is being developed to treat CLL, follicular non-Hodgkin’s lymphoma, diffuse large B-cell lymphoma, rheumatoid arthritis and relapsing remitting multiple sclerosis under a co-development and commercialization agreement between Genmab and GlaxoSmithKline. It is not yet approved for sale in any country.